How to Remove Spyware and Malware from a Windows PC

Michael Horowitz has done an excellent job of summarizing the steps necessary for removing malware (i.e., spyware, adware, viruses, etc.). He also provides links to required resources. He seems to fall into the "Reinstall the OS" camp.

Whenever I hear someone say "Reinstall the OS," I get a little hinky. Because I've done it enough and know what a pain in the ass it is, I generally regard it as a last resort. I know some people reinstall the OS once a month, but they must have more free time than I do.

Anyway, this is a good starting point.